With the medical cannabis industry becoming more commonplace, the growing methods are coming to light and allowing clients a glimpse into the operations behind the oils they consume. With the opening of the doors, comes new terms, new manufacturing methods and practices and new products that may seem a little confusing. What is this terminology, and what do they mean in terms of your medical cannabis products? 

Full Spectrum CBD Oil

Full-spectrum CBD oils are botanical oils that retain the majority of the compounds extracted from the original plant. Full-spectrum CBD oil combines all the cannabinoids found in the plant, allowing them to work in synergy with terpenes, creating an entourage effect. Since full-spectrum oils have a broader variety of molecules and terpenes remain intact during manufacturing, they have a more full-bodied taste profile and aroma compared to a one-dimensional CBD isolate product. 

Studies show that the use of full-spectrum oil extracted from the cannabis plant may be an effective treatment for chronic pain (1). While others note clients should use full-spectrum cannabis oils for its anti-inflammatory and anxiolytic effects (2,3,4). 

A full combination of compounds give a full-spectrum CBD oil a much better effect and make it a preferable option for many clients. But, full-spectrum CBD oils will always contain traces of THC. GRx’s Daybreak CBD Oil combines CBD and minimal THC to work together for an all-encompassing effect. If the client has adversity towards any amount of THC, an isolated CBD oil would be better suited. 

The Entourage Effect

The entourage effect is a chemical reaction that occurs when various cannabinoids work simultaneously when ingested, enhancing all their effects in the body (5). The term was coined by Israeli scientists Shimon Ben-Shabat and Raphael Mechoulam when they discovered that cannabinoids found in cannabis plants work similarly to the human body’s endocannabinoid system (6). This suggests a synergistic interaction between phytocannabinoids that establishes full-spectrum oils and a more effective cannabis choice.

Isolated CBD Oil

An isolate is the purest form of a compound, often preferred by medical professionals. It is produced by removing and isolating the compound from all others in that environment. When CBD isolate is produced, the purification method removes plant impurities and the majority of terpenes, leaving only the CBD cannabinoid (7). 

If you are looking for a highly concentrated CBD oil, an isolated CBD oil will be your best option. Products like GRx Sunrise, are a pure and refined CBD cannabis oil with high CBD levels and little to no traces of THC. Isolated CBD oils are a great option for those who want to experience the therapeutic benefits of CBD with only the smallest trace of THC. The extremely low levels of THC in isolated CBD oils make them non-intoxicating (8). 

Source Matters for Isolated CBD Oil

When consuming a purified oil, it must be manufactured with sustainable best practices without the use of synthetic fertilizers and pesticides. If the cannabis plant is grown with additives, this will be present in the oil. Green Relief uses organic pesticides and natural fertilizers in our growing techniques. Each batch of cannabis is tested for pesticides, microbes, heavy metals, solvent residues and other contaminants by a third party, leaving the client with the purest refined oils.


A lot of information has emerged in recent years pinning full-spectrum and isolates against each other. Neither full-spectrum nor isolated CBD oil is better than the other, it depends on the treatment target and outcomes. 

If you’re wanting more information about the products mentioned in this article, or about our growing methods here at Green Relief, please give us a call at 1-855-841-2009 or email at clientcare@greenrelief.ca.

1. Friedman D, Sirven JI. 2017. Historical perspective on the medical use of cannabis for epilepsy: ancient times to the 1980s. Epilepsy Behav. 70(Pt B):298–301.
2. Gallily R, Yekhtin Z, Hanuš LO. 2015. Overcoming the bell‐shaped dose‐response of cannabidiol by using cannabis extract enriched in cannabidiol. PP. 06(02):75–85.
3. Gallily R, Yekhtin Z, Hanuš LO. 2018. The anti-inflammatory properties of terpenoids from cannabis. Cannabis Cannabinoid Res. 3(1):282–290.
4. Ferrante C., et al. 2019. Multiple pharmacognostic characterization on hemp commercial cultivars: focus on inflorescence water extract activity. Food Chem Toxicol. 125:452–461.
5. Russo, E.B. Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br. J. Pharmacol. 2011, 163, 1344–1364.
6. Ben-Shabat S, Fride E, Sheskin T, et al. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur J Pharmacol. 1998;353(1):23-31.
7. Marinotti, O., et al. Differentiating Full-Spectrum Hemp Extracts from CBD Isolates: Implications for Policy, Safety and Science. Journal of Dietary Supplements. 2020;17(5):517-526.
8. VanDolah, H., et al. Clinicians’ Guide to Cannabidiol and Hemp Oils. Mayo Clinic Proceedings. 2019;94(9):1840-1851.


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